The plot of the fourth game in the Resident Evil series begins six years after the events of the second game. It follows Leon S. Kennedy, a former police officer now working for the United States government, as he travels to Europe on a top-secret mission to investigate the disappearance of the president’s daughter Ashley. As Leon faces horrors beyond his wildest imagination, he is compelled to discover the identity of the entity or entities responsible for everything. As Leon searches for the person or people accountable for the kidnapping of the president’s daughter, he encounters both old friends and foes at every turn of the investigation.

Compared to the previous installments, Resident Evil 4 represents a significant departure. The game utilizes a new “behind the back” movement camera angle instead of a fixed third-person perspective. Additionally, the game incorporates an “over the shoulder” aiming feature that enables players to control the movement of their gun to hit specific body parts. It has a new artificial intelligence system and more open environments, both of which make it possible for enemies to collaborate to capture and corner Leon. The adversaries are now portrayed as humans, allowing them to open doors, climb ladders, and wield weapons as they progress through the game.

Additionally, the entire item system has been reworked, so smaller items will no longer take up a whole item space when stored. In its place, a system in which things take up blocks of space in a briefcase according to size has been implemented to carry a significantly greater number of articles and weapons. When Leon defeats enemies or finds treasure in the environment, he can exchange it with the infamous “merchant” for larger briefcases, treasure maps, weapon upgrades, and more powerful weapons like the one-shot RPG.

In addition to that, there is the Mercenaries DLC for Resident Evil 3, which enables the player to participate in different survival scenarios as various characters, including Hunk and even Albert Wesker.